FEATURING DR. RONALD G. MANNING

Vice President, Standards Operations

United States Pharmacopeia

Rockville, MD

DATE THURSDAY, APRIL 15, 2004

TIME 6:00 p.m. Informal Dinner

7:00 p.m. Presentation

LOCATION U.S. PHARMACOPEIA

12701 Twinbrook Parkway, Rockville, MD 20852

ABSTRACT

Liquid Chromatographic Column Classification

Ronald G. Manning, Ph.D., Vice President, Standards Operations, United States Pharmacopeia, 12601 Twinbrook Parkway, Rockville, MD 20852-1790 (rgm@usp.org)

All L1 columns are not created equally and, hence, are not equivalent. Columns are developed for specific applications and have different:

Carbon loading

Base deactivation

End-capping

Particle shape

Packing support (silica, polymer, others)

Column design and components (PEEK, SS, others)

Can procedures developed with one column be transferred to another column?

BIOGRAPHICAL SKETCH

Ronald G. Manning, Ph.D., is vice president, standards operations for the United States Pharmacopeia (USP). He is responsible for the production of reference standards as carried out by three departments at USP: Reference Standards Evaluation (RSE, compilation and evaluation of collaborative testing studies), Reference Standards Laboratory (RSL, USP's own evaluation laboratory) and Reference Standards Production (RSP, this group handles the subdividing, processing, and packaging of reference standards). The Research and Development Laboratory (RDL), which provides analytical testing in support of USP expert subcommittees' decisions about drug standards published in the United States Pharmacopeia and the National Formulary (USP-NF), also reports to Dr. Manning. Dr. Manning joined USP in June 2000 after working for three years at the National Institutes of Health (NIH) Center for Scientific Review, Bethesda, Maryland, most recently serving as Scientific Review Administrator and Referral Officer involved in review of applications for NIH research support. Dr. Manning previously held positions of Associate Professor of Radiology at Vanderbilt University in Nashville, Tennessee, Assistant Director of Research, Mallinckrodt Medical, Inc., in St. Louis, Missouri, and Director of the Positron Emission Tomography Facility in the Nuclear Medicine Department at NIH. He earned his B.S. in chemistry and Ph.D. in physical chemistry from the University of California-Davis. Dr. Manning has published more than 50 scientific articles. He is a member of several professional organizations including the American Chemical Society, the American Association of Pharmaceutical Scientists, and AOAC International.